Genetic variation in the non-coding genome: Involvement of micro-RNAs and long non-coding RNAs in disease
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منابع مشابه
Genetic variation in the non-coding genome: Involvement of micro-RNAs and long non-coding RNAs in disease.
It has been found that the majority of disease-associated genetic variants identified by genome-wide association studies are located outside of protein-coding regions, where they seem to affect regions that control transcription (promoters, enhancers) and non-coding RNAs that also can influence gene expression. In this review, we focus on two classes of non-coding RNAs that are currently a majo...
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ژورنال
عنوان ژورنال: Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
سال: 2014
ISSN: 0925-4439
DOI: 10.1016/j.bbadis.2014.03.011